SICKLE-CELL ANEMIA:
Sickle cell anemia is when the red blood cells take on a crescent-like, sunken-in shape. Due to the shape of the cells, there is not enough oxygen circulating around the body. It happens when there is a change in one nucleotide during the DNA sequence. This change in the nucleotide eventually turns into one amino acid changing how hemoglobin proteins fold. This change in the amino acid then turns the change of shape in the red blood cell.